No hype, no nonsense truth about ebola

We all have seen and heard a lot about ebola lately. Some of it is scary, so contradictory, some confusing. In its last issue Nature took an attempt to address this topic. Read it at
http://www.nature.com/news/the-ebola-questions-1.16243

IgG 101 (C vs Fc confusion)

A lesson learned: read twice, clone once.

Recently a client asked us to fuse a gene with a human Fc. Without double checking the request we fused the requested gene with the entire human G1 constant region and delivered it to the client. You can only imagine our embarrassment when the client called and told us that we had assembled a wrong construct.

Alex

Omnirat

Hello Friends,

What do you think about the future of antibody humanization? Would we still have need for it two, three, five years from now? Would new humanized animal strains and single-cell technologies make this art obsolete? From where I stand it definitely looks like. If cloning antibodies from potent individuals has or could have some legal and moral consequences, use of humanized animals has not. The recently developed Omnirat is a huge step in this direction. Want to know more - read the original paper in the Journal of Immunology, 190:1481, 2014.

Share your thoughts.

Alex

Hello World

Hello World!

Let's start with an introduction. My name is Alex Borovkov and I'm a founder and an owner of a molecular biological service providing company called Synbuild. Synbuild founded six years ago with a help of a grant from Science Foundation of Arizona that I had received for developing of a de novo gene assembling technology while I was a professor at Arizona State University. 

As most start-ups we struggled at first, trying to find our niche. Now Synbuild a successful company focusing on antibody related molecular biological services. We have a fast growing clientele represented by a healthy mix of new and returning customers. We do everything: gene identification and sequencing; de novo gene design and assembling; gene rearrangement, modification, and modification of any sort; gene expression and much more.

We are located in Tempe, AZ and keep close ties with our alma mater - Arizona State University. We are known for our fast and reliable service and our highly competitive pricing. Over the years we optimized our protocols to the extent that such tasks as identification and sequencing of immunoglobulin genes from a hybridoma sample can be completed in one day.

We are eager to help you with your project. Please visit us at www.synbuild.com, email us at synbuild@synbuild.com or call at 480-719-3546 to tell us about your needs.

May the force be with you.

Alex